Overview
This research focuses on the mechanisms underlying collective cell movement, a phenomenon observed in various biological processes. These processes include embryonic development, wound healing, and cancer metastasis, where cells migrate in a coordinated fashion.
Research Context
Collective cell migration involves cells moving cooperatively, akin to schools of fish or flocks of birds. A fundamental question in this biological process is how individual cells, which are limited to sensing local information, manage to achieve coordination as a larger collective. The precise mechanisms facilitating this large-scale coordination have been largely uncharacterized.